Double-blind clonazepam vs placebo in panic disorder treatment
نویسندگان
چکیده
منابع مشابه
Double-blind clonazepam vs placebo in panic disorder treatment.
OBJECTIVE To assess the effectiveness of clonazepam, in a fixed dose (2 mg/day), compared with placebo in the treatment of panic disorder patients. METHOD 24 panic disorder patients with agoraphobia were randomly selected. The diagnosis was obtained using the structured clinical interview for DSM-IV. All twenty-four subjects were randomly assigned to either treatment with clonazepam (2 mg/day...
متن کاملDouble-blind acute clonazepam vs. placebo in carbon dioxide-induced panic attacks.
The inhalation of 35% carbon dioxide has consistently been shown to provoke panic attacks in panic disorder patients. We aim to determine if an acute dose of clonazepam (2 mg) attenuates the panic attacks induced by an inhalation of 35% carbon dioxide in panic disorder. Twenty-two panic disorder patients who had been drug-free for 1 week participated in a carbon dioxide challenge test 1 h after...
متن کاملVenlafaxine extended-release capsules in panic disorder: flexible-dose, double-blind, placebo-controlled study.
BACKGROUND Venlafaxine extended-release (ER) has proven efficacy in the treatment of anxiety symptoms in major depression, generalised anxiety disorder and social anxiety disorder. AIMS To evaluate the efficacy, safety and tolerability of venlafaxine ER in treating panic disorder. METHOD Adult out-patients (n=361) with panic disorder were randomly assigned to receive venlafaxine ER (75-225 ...
متن کاملTreatment-Responsiveness of Negative Symptoms in Schizophrenia: A double-blind placebo-control clinical trial
Background: The negative symptoms of schizophrenia remain a major clinical challenge. Nortriptyline is a serotonin and noradrenalin reuptake inhibitor and belongs to secondary amine tricycles. The aim of this study is to evaluate the effect of nortriptyline on the negative symptoms of schizophrenia. Methods: This study is a six-week randomized placebo-control trial of nortriptyline or placebo a...
متن کاملSertraline in the treatment of panic disorder: a double-blind multicenter trial.
OBJECTIVE This study determined the efficacy and safety of sertraline in the treatment of patients with panic disorder. METHOD The study was a randomized, double-blind, parallel-group, flexible-dose comparison of sertraline and placebo in outpatients with a DSM-III-R diagnosis of panic disorder with or without agoraphobia. After a 2-week single-blind placebo lead-in, 168 patients entered a 10...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Arquivos de Neuro-Psiquiatria
سال: 2000
ISSN: 0004-282X
DOI: 10.1590/s0004-282x2000000600008